Our mission is to understand the molecular basis of psychiatric disorders that increase the risk of suicide.
We are using a reverse translational approach to elucidate the pathophysiology of psychiatric disorders. Initially we investigate gene expression in postmortem brain from cohorts of individuals with schizophrenia, bipolar disorder and major depression, including cases of suicide. Our recent work revealed that an epitranscriptomic process known as RNA editing, is elevated in the dorsolateral prefrontal cortex (DLPFC) of depressed suicides. Following these studies of human brain, we are testing the effects of stress on mouse behavior and neurochemistry. RNA editing regulates brain development and synaptic plasticity, which are impaired in psychiatric disorders, including schizophrenia and depression. Our results suggest that prenatal stress triggers abnormalities in the glutamate system and in RNA editing, which may be precursors for psychiatric illness. We have consistently identified sex differences in these data. The objective of this research is to identify new targets for improved therapeutic interventions and to discover biomarkers with which we can predict suicidal behavior, so that preventative strategies can be developed.
Training Opportunities in the Sodhi Lab:
Students, fellows or residents who join Dr. Sodhi’s lab can expect to receive training in molecular genetics, gene expression studies of rodent or human tissue, behavioral pharmacology, mammalian cell culture, in addition to gaining expertize in the broader area of the neuropharmacology of schizophrenia, mood disorders and suicide.
Descriptions of some of our projects are below.
Epitranscriptomic basis of resilience to psychological stress.
understanding the molecular basis of cognition and emotion
The overall goal of this project is to understand the molecular pathways that increase resilience to stressful life events. It is established that mental illness runs in families (genetics) and that mental illness is triggered or exacerbated by environmental stress. We are testing the effects of psychological stress on behavior, and on the expression of genes in specific brain regions that are important in learning, memory and anxiety behaviors.
Sex differences in major depression and suicide
Studies of glutamatergic pathways
Gene expression analyses reveal that female patients with depression may have elevated expression of glutamate receptor genes in the dorsolateral prefrontal cortex. This region is important for executive function and implicated in response to antidepressant therapies including TMS. Both males and females who died by suicide appeared to have increased expression of specific glutamatergic genes: the genes encoding GluN2B (GRIN2B), GluK3 (GRIK3) and mGluR2 (GRM2) and specific glutamate transporters. These data indicate that the glutamatergic system may contain many targets for antidepressant drug development. The glutamate synapse is illustrated on the left.
Glutamatergic genes in schizophrenia
Studies of the glutamate system in the thalamocortical circuitry
Accumulating data support the glutamate hypothesis of schizophrenia. Our investigations have led to the discovery of reduced expression of glutamatergic genes in laser-captured relay neurons of the medial dorsal thalamus (pictured on the right). These results indicate that the thalamocortical circuitry is disrupted in schizophrenia, perhaps underpinning the disorganized thought exhibited by schizophrenia patients.
Neuronal morphology predicts mental health
Dendritic branching, spine density and morphology are measures of the number, strength, and stability of synaptic contacts. These morphological features are predictors of cognitive function and mental health. We are measuring variations in neuronal morphology in mice exposed to psychological stress. The neuron pictured is from the CA1 region of the mouse hippocampus.
Identification of predictors of suicide risk.
Analyses of psychiatric patient populations
The overall goal of this project is to develop an objective method to assess suicide risk. The rate of suicide has steadily increased over the past decade, with over 44,000 deaths per year. Large epidemiological studies have identified a number of risk factors for suicidal behavior in adults and key amongst them are preexisting mental illnesses, particularly mood disorders and depression, impulsivity, hopelessness, anhedonia and insufficient coping strategies during stressful events. Tragically, many patients do not report that they are suicidal and therefore fail to receive appropriate treatment. We could reduce the frequency of suicide if we had an objective means to identify patients who are at high risk, so that these patients are targeted for immediate and intensive psychiatric treatment. In this project, we plan to develop a blood test for suicide risk, including genetic and inflammatory biomarkers.
Monsheel Sodhi Ph.D.
Monsheel received her Pharmacy degree, MSc in Neuroscience and Ph.D. in Genetics from the University of London (U.K.). Her postdoctoral training in Molecular Neuropathology was at the University of Oxford, followed by postdoctoral training in Neuropharmacology at Vanderbilt University. Her major research interest is to unravel the molecular pathophysiology of major psychiatric disorders, and in doing so, identify novel targets for drug development and biomarkers for improved diagnostic tools.
Tristram Buck B.S.
Tristram Buck is a student in the IBPS Ph.D. program at Loyola University Chicago. Tristram received his Bachelors of Science degrees in Psychology and Neuroscience at Syracuse University. He completed his post-baccalaureate training at NIDA in Dr. Eliot Gardner’s Neuropsychopharmacology lab. His current research focuses on elucidating gene expression pathways disrupted by environmental stress that lead to deficits in cognition and reward.
Elaina Wilkens B.S.
Student Physician Scientist
Elaina is currently a first-year medical student at Stritch School of Medicine. She received her bachelor's degree from University of Illinois Urbana-Champaign in Psychology-Behavioral Neuroscience and Molecular and Cellular Biology. Elaina is working in the Sodhi Laboratory on a project focused on the impact of stress on RNA editing.
Kristeen Bebla B.S.
Kristeen is a biochemistry major at Loyola University Chicago. Kristeen is performing molecular docking analyses in a project focused on drug discovery. Her goal is to study medicine after graduation.
Allison is a nurse studying in the undergraduate program in Neuroscience at Loyola University. Allison is collaborating with the Sodhi Laboratory in a project investigating the effects of stress on learning and memory in mice. Allison's goal is to study medicine after graduating.
Brian Powers Ph.D.
Staff Scientist 2018-19
Brian received his Ph.D. at UIUC and completed postdoctoral training at Cornell University. Brian's research focus is behavioral analyses of rodents. Brian published one first author paper during his training at the Sodhi Laboratory. He is currently training in the Kartje lab at the Hines VA.
Lauren Haar Ph.D.
Postdoctoral Scientist 2018
Lauren is skilled in RNA Biology and conducted postdoctoral studies of the effects of stress on RNA editing and microRNA biogenesis. Lauren completed her Ph.D. at the University of Cincinnati in the laboratory of Keith Jones. After leaving the Sodhi lab, Lauren joined the University of North Carolina, where she is Assistant Professor of Chemical Biology and Medicinal Chemistry.
Greg Bristow D. Phil.
Postdoctoral scientist 2014-16
Greg received his doctoral training at the University of Oxford Department of Psychiatry and completed postdoctoral training in the Sodhi Lab. Greg is interested in investigating the molecular basis of cognitive dysfunction in the human brain. Greg has published 2 first author papers (Journal of Affective Disorders, Schizophrenia Research) and has two papers in preparation. He is currently a member of the faculty of Pharmacology at the University of Bradford, U.K.
Evelyn Nwabuisi-Heath Ph.D.
Postdoctoral Scientist 2013-2015
Evelyn's postdoctoral training was in assay development for high throughput drug screening and in the analysis of RNA editing in animal models of psychiatric illness, from which she achieved a first author publication. Evelyn is now working for Takeda Pharmaceuticals in Clinical Research.
Angel Gray-Shah Ph.D.
Postdoctoral Scientist 2012-14
Angel completed both her BS in Psychology and Neuroscience and her PhD at Loyola University Chicago, IL. Her research on the molecular mechanisms of depression and suicide resulted in a first author publication in Molecular Psychiatry in 2015. Angel is currently in a leadership role at Community Therapy Services.
Ania Bobrowska Ph.D.
Postdoctoral Scientist 2012
Ania completed an MSc in Molecular Biology at the International Max Planck Research school in Goettingen, Germany and her PhD at King's College London, UK. Anna studied RNA editing and its role in learned helplessness while in the Sodhi Laboratory. Anna currently works at Costello Medical in Cambridge (UK) as Deputy Head of Literature Reviews and Synthesis.
Krista Lotesto B.S.
Research Assistant 2019-2020
Krista joined the Sodhi laboratory in 2019 and is conducting analyses of the long term effects of stress on behavior and gene expression. Her skills include tests of spatial memory and behaviors correlating with anxiety. Krista has co-authored 1 paper with the Sodhi Laboratory. Krista has transitioned to a role at the VA, focusing on traumatic brain injury.
Shivesh Ghura M.S.
Graduate Research Specialist 2017
Shivesh joined the Sodhi Laboratory in 2017 and contributed molecular studies of PTSD, focusing on the hippocampus in a rat model of PTSD. Shivesh is currently a Ph.D. student in the graduate program in Pharmacology at University of Pennsylvania.
Madiha Khan B.S.
Pharm.D. Student 2015-16
Madiha contributed to several research projects in the Sodhi Laboratory in 2015. Madiha is completed her PharmD at the UIC College of Pharmacy. After working as a Clinical Project Manager & Lead PharmD Preceptor at MedLogix Communications, LLC. she has transitioned to Senior Associate Scientific Director at the Lockwood Group.
Michelle Vierra-Balakrishnan B.S.
Research Specialist 2013
Undergraduate student 2012
Michelle joined the Sodhi lab in January 2012 and earned her Bachelor of Science degree in Biological Sciences. She studied the expression of ADAR enzymes in psychiatric disorders in the Sodhi lab. She is co-author on two papers in preparation and won a Society for Neuroscience Travel Award for her research in 2013. She is currently a manager in marketing for Pacific Biosciences in California.
John A. Bostrom M.D.
Research Specialist 2011-12
Summer Student 2010
Jack joined the lab in the summer of 2010 and graduated from Gettysburg College in May 2011 with a BS in Biology and a minor in Chemistry. He continued research in the Sodhi Lab as a Research Specialist in 2011-12, before joining Medical School at UMASS. Jack wrote two first author publications as a result of his research and he is currently completing his residency in Internal Medicine at NYU.
Daniel Mount B.S.
Research Assistant 2010-2011
Daniel graduated from UAB with a BS in Psychology. He has conducted a variety of genetic and transcriptional experiments in postmortem human tissue and drug-treated animals in the Sodhi Lab. He is currently a graduate student in Alabama.
Kimberly Wood Ph.D.
Research Assistant 2007-2008
Kimberly trained as a Research Assistant in the Sodhi Lab. Her experiments included gene expression analyses of the GABAergic system in the thalamus and anterior cingulate cortex in postmortem subjects with schizophrenia. Kimberly's work resulted in one co-authored paper, and several posters at scientific conferences, including the Society for Neuroscience annual meeting. After completing her Ph.D. at UAB, Kimberly accepted a position as a clinical assistant professor at Samford University.
Micah Simmons M.S.
Research Assistant 2007-2009
Micah graduated from UAB with a MS in Genetics. He conducted a variety of genetic and transcriptional experiments in postmortem human tissue and drug-treated animals in the Sodhi Lab. Micah co-authored 2 publications with the Sodhi Laboratory. He is currently working at Southern Research’s Neuroscience Drug Discovery Division.
Future scientific leaders!
Rachel Mazurek B.S.
Graduate Student 2021
Rachel is a graduate student in the Loyola IPBS program and recently completed a rotation in the Sodhi Lab. Her interests include neuroinflammation and infectious disease.
Undergraduate Student 2020-2021
Krishna joined the lab as part of the IMSA program while in high school. Krishna is working on a project including RNAseq analysis of subjects with psychiatric illness. Krishna has won first and second place in two consecutive Brain Bee competitions in Illinois, and he joined Dartmouth College in the Fall of 2020. His long-term goal is to study medicine.
Undergraduate Student 2021
Andrew is working with the Sodhi Lab in collaboration with the Miller Lab in an in silico drug discovery project. Andrew's goal is to study medicine after he graduates from Notre Dame University.
Undergraduate Student 2021
Jaap is investigating the effects of prenatal stress and social isolation on learning and memory in mice, with the goal of identifying which molecular pathways mediate the long term effects of stress on behavior. Jaap is majoring in Systems Biology and Computer Science at Case Western University.
Mackenzie Smith B.S.
Graduate Student 2020
Mackenzie is a graduate student in the IPBS Ph.D. program at Loyola. She completed a rotation in the Sodhi Laboratory that included testing the levels of RNA editing in human hippocampus. Mackenzie joined the Gogliotti lab in 2021.
Jake Exline B.S.
Graduate Student 2020
Jake conducted research on RNA editing in the Sodhi Lab during his rotation in the Masters in Biochemistry program at Loyola. Jake is very interested in studying traumatic brain injury (TBI), and is completing his MS project focused on treatments for TBI at the VA Hines.
Chris Hoover B.S.
Graduate Student 2018
Chris is a graduate student of the IPBS Ph.D. program at Loyola, and has completed a rotation in the Sodhi Laboratory. Chris assisted in optimizing hippocampal slice culture protocols and performed pilot tests of the effects of fluoxetine and corticosterone on the hippocampus.
McKenna BeLow B.S.
Graduate Student 2018
McKenna is a graduate student of the IPBS Ph.D. program at Loyola. She successfully completed a rotation in the Sodhi Laboratory where she assisted in optimizing hippocampal slice culture protocols and performed pilot tests of the effects of estrogen on the hippocampus after exposure to corticosterone.
Michael Long B.S.
Graduate Student 2018
Michael Long is a graduate student in the IPBS Ph.D. program at Loyola. He completed a rotation in the Sodhi Lab, focused on RNA editing in the hippocampus of a rat model of PTSD. Mike is now conducting research into ARC protein function in the neuron.
Will Zhang B.S.
Graduate Student 2017
Will is a graduate student in the IPBS program at Loyola. Will completed a rotation project in the Sodhi Laboratory including studies of RNA editing in the rat hippocampus.
Arthur Segismundo B.S.
Graduate Student 2017
Arthur is a student in the MS in Neuroscience Program at Loyola University. Arthur is contributing to ongoing studies of in silico molecular modeling in the Sodhi Laboratory. Arthur presented his research at the Chicago Society for Neuroscience and the Society for Biological Psychiatry annual meetings. Arthur's goal is to be a physician scientist.
Wenyi (Chris) Qin Ph.D.
Graduate Student 2012-2018
Chris was a graduate student of Bioengineering and worked with the Sodhi Laboratory on a project focused on identifying gene expression signatures of schizophrenia. Chris co-authored 1 paper with the Sodhi Laboratory and received his Ph.D. in January 2018. Chris is currently a postdoctoral fellow at Yale University.
Brittany Jones B.S.
Undergrad Student 2015-16
Brittany participated in laboratory research during her undergraduate studies. She is currently in the Neuroscience graduate program at Georgetown University.
Banafshe Samani M.S.
Graduate Student 2014-2016
Banafshe joined the Sodhi Lab in 2014. She investigated RNAseq data in psychiatric illness and is currently pursuing doctoral level training in the Dept. of Chemistry at UIC.
Sarah Khan B.S.
Undergrad Student 2015-16
Sarah Khan contributed to laboratory research in 2015-16, including molecular genetic analyses, during her senior year. She is now pursuing a graduate degree in Dentistry.
Sarah Schram Ph.D.
Graduate Student 2014
Sarah completed a rotation in the Sodhi Laboratory in 2014, focusing on laser capture microdissection of postmortem human brain. She is currently a Ph.D. student in the laboratory of Jeff Loeb at UIC.
Julie Do B.S.
Julie performed undergraduate research in the Sodhi lab and graduated with a B.S. in Biochemistry in 2014. She is currently pursuing a Pharm D at the UIC College of Pharmacy.
Jennifer Melbourne Ph.D.
Graduate Student 2013
Jenni joined the Sodhi Lab during 2013 and is interested in the mechanisms underlying schizophrenia and psychosis. She completed her undergraduate degree in Neuroscience at Cardiff University and her Master's degree in Mind, Language, and Embodied Cognition at the University of Edinburgh. She recently received her PhD in Neuroscience at UIC.
Yoshimi Nomura B.S.
Undergraduate Scientist 2013
Yoshimi conducted undergraduate research focused on glutamate receptor gene expression in psychiatric illnesses. She is pursuing a PharmD degree at UIC.
Nathan Wray B.S.
Graduate Student 2014
Nathan is a graduate student of the Neuroscience Program and completed a rotation in the Sodhi Laboratory in 2014. He received his Ph.D. at UIC and is currently working as a Medical Science Liaison (MSL) for Collegium Pharmaceuticals.
Sean Munoz M.D.
Medical Student Scientist
Sean completed his MD at the UIC College of Medicine. He is interested in neuroscience research regarding the underlying molecular mechanisms of psychiatric disorders and aspires to be a physician-scientist. Sean has completed the pediatrics residency program at Rush University.
Julie Bucek Pharm.D.
Julie trained at the UIC College of Pharmacy. She is interested in pharmacogenetics and its relevance to the treatment of depression. Julie is currently a pharmacist working in the VA system in Illinois.
Kavita Nadendla M.D.
Undergraduate Student 2010-11
Kavita has conducted research on RNA editing in the Sodhi Lab. She was awarded the distinction of Outstanding Student for 2012 by the UAB Undergraduate Neuroscience Program. She completed her medical degree at UAB in 2016 and is doing her residency training at Rhode Island Hospital.
News and media
Achievements, collaborations and conferences
Society for Biological Psychiatry, 2022
New Orleans, LA
In-person conference for the SOBP was a roaring success! Hope to see more international delegates at next year's meeting in San Diego.
American College of Neuropsychopharmacology, 2021
San Juan, Puerto Rico
First in-person meeting attendance since the COVID-19 shutdown!!!! As ever, ACNP is an excellent conference and integration of virtual attendees was well done. The photo depicts the 'Centro de Convenciones de Puerto Rico'.
Society for Biological Psychiatry, 2021
Monsheel Sodhi and Tristram Buck attended the virtual conference of the Society for Biological Psychiatry. This picture shows Monsheel's avatar visiting posters at Gathertown.
Chicago Soc for Neuroscience, 2021
Monsheel Sodhi chaired the afternoon symposium of the virtual annual meeting of the CSFN. The symposium was entitled 'Novel Therapeutic Strategies for CNS Disorders'.
Neurotherapeutics Discovery and Development at the National Institute for Drug Abuse (NIDA), Bethesda, MD. This meeting took place immediately before the COVID-19 shutdown in March 2020 .
St. Albert's Day, 2019
Krishna Nair presents his research at the annual research day at Loyola University Chicago.
St. Albert's Day, 2019
Krista Lotesto presents her poster at the annual St. Albert's Day Forum at Loyola University Chicago.
Society for Neuroscience, 2019
Sodhi Lab presents 3 posters at the Society for Neuroscience Annual Meeting. From the left: Krista Lotesto, Monsheel Sodhi, Brian Powers.
Society for Biological Psychiatry 2019
Brian Powers and Monsheel Sodhi present 3 posters at the SOBP annual meeting.
Chicago Soc for Neuroscience, 2019
Krishna Nair receives a prize for the Brain Bee competition in Illinois for the third consecutive year.
Society for Neuroscience 2018
San Diego, CA
Monsheel Sodhi and former UAB colleagues at the McKnight social, SFN. From the left: Kristina Visscher, Monsheel Sodhi, Diane Tucker, Linda Overstreet-Wadiche
Chicago Society for Neuroscience 2018
Arthur Segismundo presented his poster at the CSFN in Chicago on March 23rd 2018.
Society for Neuroscience 2016
San Diego, CA
Sodhi lab poster presentation to Joel Kleinman and Schahram Akbarian.
Society for Biological Psychiatry, 2016
Greg Bristow presented his research at the poster exhibition, while Monsheel Sodhi chaired a research symposium entitled 'Sex differences in depression and antidepressant response', which included a platform presentation. The photo depicts the interior design of the conference hotel (photos of the conference presentations are pending).
UI Center on Depression and Resilience, 2015
Evelyn Nwabuisi-Heath presenting her research to Patrick J. Kennedy II.
The findings reported add to growing support for the strategy of targeting glutamate receptors in the treatment of depression and suicidal behavior. Moreover, these findings may have implications for differential treatment response in males and females treated with antidepressants targeting the glutamate system.
This press release reports the findings of our research in 2015.
Depressed Females have Overactive Glutamate Receptor Genes
Article by PsyPost in Mental Health
American College for Neuropsychopharmacology, 2015
Our poster was only 3 votes away from winning the best poster prize of the ACNP!
Society for Neuroscience, 2015
The Sodhi Lab presented three posters at the SFN annual meeting. This photo shows Greg Bristow presenting his research poster.
GRC RNA Editing Conference 2015
Il Ciocco, Italy
Photo of attendees at the Gordon Research Conference on RNA Editing.
Society for Neuroscience, 2014
Evelyn Nwabuisi-Heath presenting her poster. This research was extended to include studies of prenatal stress in an animal model and won a Chicago Society for Neuroscience poster award in 2014. Evelyn also presented her poster at the annual Society for Neuroscience meeting in Washington DC. Moreover, Evelyn received a CBC postdoctoral award in 2014 for this project.
Student Research Forum 2013
Yoshimi Nomura, presentation of undergraduate research at the UIC Student Research Day.
Vahlteich Research Award 2013
Award presented by Prof. Greg Thatcher for the project: 'Discovering Novel Targets for the Treatment of Major Depression'.
GRC RNA Editing Conference 2013
Formal photo of attendees at the Gordon Research Conference on RNA Editing.
Society for Neuroscience, 2013
San Diego, CA
Michelle Vierra is pictured performing gel electrophoresis in the photo. Michelle received an undergraduate award for her work in the Sodhi Laboratory, which was focused on measuring splice variation in postmortem brain from psychiatric patients. Michelle also received a travel award to attend the Society for Neuroscience in 2013 to present this work in an oral session. Michelle is currently a marketing manager or Pacific Biosciences in California.
American College of Neuropsychopharmacology, 2011
Monsheel Sodhi networking with colleagues and collaborators at the annual ACNP meeting.
The Impact of RNA Editing on Suicide Risk
News interview on receipt of an American Foundation for Suicide Prevention Young Investigator Award. 2009-11.
Undergraduate Research Forum, 2010
SIBS Summer Program Student, Jack Bostrom, received first prize for his poster. He subsequently published this work in the journal Schizophrenia Research.
2010-2022 (from a total of 31 papers)
Sex differences in the transcription of monoamine transporters in major depression.
South Loop social after Society for Neuroscience seminars
Kristina Visscher and Monsheel Sodhi
Selfie with ex-colleagues from UAB schizophrenia labs
Teri Mueller, Monsheel Sodhi, Adrienne Lahti
Bowling and bocce social 2019
No photoshop on this selfie!
Clockwise from the left: Monsheel Sodhi, Krista Lotesto, Susan Uprichard, Brian Powers, Will Zhang
Joel Kleinman hard at work at NIMH
Joel is a marvelous collaborator!
Julie and Evelyn in the lab
Julie Do, Evelyn Nwabuisi-Heath
Monsheel Sodhi aliquoting cDNA
AFSP Out of the Darkness Walk, Chicago, IL
Sodhi Lab, friends and collaborators attend the American Foundation for Suicide Prevention Walk in Grant Park, Chicago.
Clockwise from left: Monsheel Sodhi, Julie Vanderweghe, Scott Langenecker, Angel Gray-Shah, Michelle Vierra-Balakrishnan, Sara Weisenbach.
Michelle and Sean between experiments
Michelle Vierra, Sean Munoz
Agarose gel electrophoresis by Michelle Vierra
Lab social in Little Italy
Sean Munoz, Michelle Vierra, Angel Gray-Shah
Clockwise from the left: Julie Do, Evelyn Nwabuisi-Heath, Michelle Vierra, Skylar Carson, Sean Munoz, Angel Gray-Shah
Clockwise from the left: Michelle Vierra, Sean Munoz, Angel Gray-Shah, Evelyn Nwabuisi-Heath, Julie Do
Call to Action: Neuroscience Research
The brain is the final frontier of the life sciences. Investigating the brain in health and disease is where you can have the most impact. The questions are profound, the illnesses are fascinating, and we finally have tools with which we can make unprecedented progress. Although mental illness is the leading cause of disability and death globally, we still lack effective treatments for psychiatric and neurological disorders. This is an invitation to join us in our work to improve our understanding of the molecular basis of mental illness!
M.S. and ph.d. students
Monsheel Sodhi is a member of the graduate faculty and is actively recruiting students from the Ph.D., MD/ Ph.D. and MS programs at Loyola University. Trainees from the Sodhi Laboratory have published in high impact journals, received research awards (SfN, CBC, CSfN) and have been able to leverage the training and experience received in our laboratory to make progress towards their career goals. Mentoring students is a priority in our research team. Please contact Dr. Sodhi for more information about projects and application procedures email@example.com.
Research Assistant Opportunities in Molecular Psychiatry: 2022
Employer: Loyola University Chicago, Stritch School of Medicine.
The Department of Molecular Pharmacology and Neuroscience at Loyola University Chicago is recruiting graduate scientists for a project investigating stress-related psychiatric illness.
Description: We are seeking highly motivated and creative scientists to join a dynamic research team exploring fundamental questions about the molecular basis of psychiatric illness, using both basic science and clinical translational approaches. Projects will be data-driven, using a reverse translational approach. We aim to consolidate data generated from human studies (including investigations of postmortem human brain) using animal models and cell culture. Our projects provide opportunities to become proficient in state-of-the-art techniques such as next generation sequencing, gene editing, behavioral pharmacology and eQTL analysis.
Our laboratory is within the new, state-of-art Center for Translational Research and Education at the Health Sciences campus of Loyola University, located close to the downtown area of Chicago, with excellent public transport. The University provides a generous benefits package (for more information please see http://www.luc.edu/hr/uahprogram.shtml).
Qualifications: Candidates who have graduated with a BS degree within the last 2 years, with research experience in the laboratory are encouraged to apply. Proficiency in one of the following areas is essential: genomics, neuroanatomy, cell biology and behavioral pharmacology. Good verbal and written communication skills in English are also essential. The PI will provide mentoring, supervision and intensive training.
To apply: Interested individuals should email a CV/ resume and cover letter including details of research experience and career goals to firstname.lastname@example.org. Informal enquiries are welcome. The positions will remain open until filled.
Loyola University Chicago is an equal opportunity employer. We encourage minorities, women, veterans and individuals with disabilities to apply.